Sandrine Hugues-Ascery

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Sandrine Hugues-Ascery, Head of in vivo electrophysiology platform

PhD, Doctor in Neurosciences

Sandrine is Chief Scientist of the In vivo electrophysiological platform at E-PHY-SCIENCE. Trained as a neurophysiologist Sandrine has more than 15 years of experience in vivo electrophysiology (single and multi-electrode recordings).

Sandrine completed a PhD in Neurosciences from the University of Nice Sophia-Antipolis (France). She then completed two post-doctoral fellowships in France. During her PhD and post-doctoral fellowships, Sandrine empowered her skills and experience on in vivo electrophysiological techniques and behavioral tasks.

Sandrine joined E-PHY-SCIENCE in 2014.

Selected publications

Fanny Eysert, Audrey Coulon, Emmanuelle Boscher , Anaїs-Camille Vreulx, Amandine Flaig, Tiago Mendes , Sandrine Hugues, Benjamin Grenier-Boley, Xavier Hanoulle, Florie Demiautte, Charlotte Bauer, Mikael Marttinen, Mari Takalo, Philippe Amouyel, Shruti Desai, Ian Pike, Mikko Hiltunen, Frédéric Chécler, Mélissa Farinelli, Charlotte Delay, Nicolas Malmanche, Sébastien S Hébert, Julie Dumont, Devrim Kilinc, Jean-Charles Lambert, Julien Chapuis 

Alzheimer’s genetic risk factor FERMT2( Kindlin-2) controls axonal growth and synaptic plasticity in an APP-dependent manner.

Molecular Psychiatry 2020
Jérémy Camon, Sandrine HuguesMelissa A ErlandsonDavid RobbeSabria LagounEmna MarouaneIngrid Bureau The Timing of Sensory-Guided Behavioral Response is Represented in the Mouse Primary Somatosensory Cortex. Cereb cortex 2019
Rosselet Céline, Fieschi Maxime , Hugues Sandrine, Bureau Ingrid Associative learning changes the organization of functional excitatory circuits targeting the supragranular layers of mouse barrel cortex. Frontiers in neural circuits 2011
Fleuriet Jérome,  Hugues Sandrine, Perrinet Laurent, Goffart Laurent Saccadic foveation of a moving visual target in the rhesus monkey. Journal of Neurophysiology 2011
Hugues Sandrine, Garcia René Reorganization of learning-associated prefrontal synaptic plasticity between the recall of recent and remote fear extinction memory. Learning and Memory. 14:520-524 2007
Hugues Sandrine, Garcia René, Léna Isabelle Time course of extracellular catecholamine and glutamate levels in the rat medial prefrontalcortex during and after extinction of conditioned fear. Synapse 2007
Hugues Sandrine, Chessel Aline, Lena Isabelle, Marsault Robert, Garcia René. Prefrontal infusion of PD098059 immediately after fear extinction training blocks extinction-associated prefrontal synaptic plasticity and decreases prefrontal ERK2 phosphorylation. Synapse 2006
Farinelli Mélissa, Deschaux Olivier, Hugues Sandrine, Thevenet Aurélie, Garcia René Hippocampal train stimulation modulates recall of fear extinction independently of prefrontal cortex synaptic plasticity and lesions. Learning and memory 2006
Hugues Sandrine, Deschaux Olivier, Garcia René Postextinction infusion of a mitogen-activated protein kinase inhibitor into the medialprefrontal cortex impairs memory of the extinction of conditioned fear. Learning and Memory 2004
Hugues Sandrine, Kessal Karima, Hunt Mark J, Garcia René A conditioned stressful environment causes short-term metaplastic-like changes in the rat nucleus accumbens. Journal of Neurophysiology 2003

Full texts availables on request.